Guidelines & Prescription Refill
Thank you for choosing Klearmind Clinics
Oral Ketamine Guidelines
Now that the initial process of interviews and paperwork is complete, we can proceed with your treatment. We appreciate your trust in us for your mental health and well-being and remind you of the importance of safely securing your oral medications, which are intended solely for your use.
We recognize your commitment to improving your mental health through guided therapy. The guidelines below cover safety, potential side effects, steps for obtaining medication refills, and contact information. Before beginning treatment, please review the signed contract carefully. Should you have any questions, do not hesitate to reach out to us.
Purpose
To support the safe and appropriate administration of ketamine for therapeutic purposes, while providing guidelines to help prevent potential adverse effects, and to continually evaluate each patient’s response to treatment.
Please note that ketamine-induced cystitis, characterized by bladder issues like urinary incontinence and painful urination, is a potential long-term side effect, typically associated with the drug's chronic misuse.
Contraindications
Ketamine therapy may not be suitable for individuals with the following conditions:
- Active substance misuse, including prescription medications, alcohol, or illicit drugs. History of psychosis.
- Active suicidal ideations or plans.
- Untreated head injury with increased intracranial pressure.
- Pregnancy or breastfeeding. Allergy to Ketamine.
- Prior poor response to Ketamine. Poorly controlled blood pressure. History of nausea or vomiting.
Learn More About Ketamine
Ketamine is a synthetic medication that was initially used as an adjuvant to anesthetics in the 1960s. It has been used in the Vietnam war to reduce physical pain due to injuries. At higher dosages, it is used in the operating and emergency rooms for surgeries as a large part of an anesthetic regimen.
In the 1970s, Ketamine was approved by the FDA as an anesthetic and since has been used around the world in humans and animals. It is a safe and successful anesthetic used in hospitals, dentist offices, and veterinary and medical clinics since its development.
Within the past several decades years, Ketamine was identified as having beneficial effects on patients with Obsessive-Compulsive Disorder, Post Traumatic Stress Disorder, Postpartum Depression, Major Depressive Disorder, Treatment-Resistant Depression (TRD), and Suicidality (need reference).
Depression is the leading cause of disability around the world. In the United States, over 16 million adults experience major depression within the course of a year. Between 1999 and 2016, depression- related suicide rates increased by over 30% (reference).
What our customers want to know
What is ketamine-assisted therapy, and how does it work?
Ketamine-assisted therapy combines the use of ketamine, a dissociative anesthetic, with psychological support. Sessions are conducted in person under the supervision of trained clinicians following a thorough evaluation. Ketamine is used to support a state that can facilitate exploration and processing of emotions and memories during therapy. It is thought to affect certain receptors in the brain and support neuroplasticity, which may allow for new insights during therapy.
What conditions or issues can be addressed with ketamine?
Under the supervision of a qualified physician or therapist, ketamine-assisted therapy is used to help manage a range of mental health conditions, which may include treatment-resistant depression, anxiety disorders, post-traumatic stress disorder (PTSD), and obsessive-compulsive disorder (OCD). Suitability is determined on an individual basis following a physician evaluation, and individual responses vary.
What is the difference between IV and Oral Ketamine at Klearmind Clinics?
At Klearmind Clinics, IV Ketamine offers a faster, more intense effect under medical supervision, while Oral Ketamine provides a gentler, more gradual experience during in-person, clinician-supervised sessions; the most appropriate option depends on your needs and your clinician’s recommendation.
What are the common side effects of oral ketamine?
The most common side effects of oral ketamine are nausea and dizziness, which can be managed with precautions like taking it with food, using prescribed anti-nausea medication (Zofran), and following clinician guidance.
How are medications provided during treatment?
Medications used as part of your treatment are dispensed and administered during your in-person clinic visits, as determined by your treating physician. There is no remote or mail-order administration.

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